Effects of subthalamic nucleus stimulation on characteristics of EMG activity underlying reaction time in Parkinson's disease
Identifieur interne : 003D26 ( Main/Exploration ); précédent : 003D25; suivant : 003D27Effects of subthalamic nucleus stimulation on characteristics of EMG activity underlying reaction time in Parkinson's disease
Auteurs : Hatice Kumru ; Christopher Summerfield ; Francesc Valldeoriola ; Josep Valls-SoléSource :
- Movement Disorders [ 0885-3185 ] ; 2004-01.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Aged, Brain Mapping, Choice Behavior (physiology), Electric Stimulation, Electric Stimulation Therapy, Electromyography, Female, Functional Laterality (physiology), Hand (innervation), Humans, Male, Middle Aged, Muscle, Skeletal (innervation), Nervous system diseases, Parkinson Disease (physiopathology), Parkinson Disease (therapy), Parkinson disease, Parkinson's disease, Pattern Recognition, Visual (physiology), Psychomotor Performance (physiology), Reaction Time (physiology), Reaction time, Subthalamic Nucleus (physiopathology), Subthalamic nucleus, Treatment Outcome, ballistic movements, deep brain stimulation, reaction time.
- MESH :
- innervation : Hand, Muscle, Skeletal.
- physiology : Choice Behavior, Functional Laterality, Pattern Recognition, Visual, Psychomotor Performance, Reaction Time.
- physiopathology : Parkinson Disease, Subthalamic Nucleus.
- therapy : Parkinson Disease.
- Aged, Brain Mapping, Electric Stimulation, Electric Stimulation Therapy, Electromyography, Female, Humans, Male, Middle Aged, Treatment Outcome.
Abstract
We examined the effects of high‐frequency deep brain stimulation of the subthalamic nucleus (STN‐DBS) on characteristics of electromyographic (EMG) activity of the agonist muscle in 8 patients with Parkinson's disease (PD). Patients were examined during STN‐DBS (ON), and 30 minutes after switching off both stimulators (OFF). They were asked to make a ballistic movement in paradigms of simple reaction time (SRT) and choice reaction time (CRT) tasks. Onset of movement (MOVonset) was measured as the latency of the initial displacement from baseline of the signal from an accelerometer attached to the dorsum of the hand. In the associated EMG activity, recorded from wrist extensor muscles, we measured onset latency (EMGonset), size of the first EMG burst (EMGsize), and number of EMG bursts (EMGbursts) counted between EMGonset and task execution. MOVonset and EMGonset were significantly shorter in ON than in OFF conditions in CRT. EMGsize was larger, EMGbursts were reduced, and peak of the acceleration profile was larger in ON compared with OFF conditions in both SRT and CRT. Our results indicate that STN‐DBS induces a significant improvement in motor performance of reaction time tasks in PD patients. Such improvement is associated with a change in features of the EMG activity suggesting an increase in the excitability of the motor pathways engaged in ballistic movements. © 2003 Movement Disorder Society
Url:
DOI: 10.1002/mds.10638
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001021
- to stream Istex, to step Curation: 001021
- to stream Istex, to step Checkpoint: 002707
- to stream PubMed, to step Corpus: 003570
- to stream PubMed, to step Curation: 003570
- to stream PubMed, to step Checkpoint: 003472
- to stream Ncbi, to step Merge: 000C94
- to stream Ncbi, to step Curation: 000C94
- to stream Ncbi, to step Checkpoint: 000C94
- to stream Main, to step Merge: 005684
- to stream PascalFrancis, to step Corpus: 002226
- to stream PascalFrancis, to step Curation: 000A95
- to stream PascalFrancis, to step Checkpoint: 002162
- to stream Main, to step Merge: 005A00
- to stream Main, to step Curation: 003D26
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effects of subthalamic nucleus stimulation on characteristics of EMG activity underlying reaction time in Parkinson's disease</title><author><name sortKey="Kumru, Hatice" sort="Kumru, Hatice" uniqKey="Kumru H" first="Hatice" last="Kumru">Hatice Kumru</name></author><author><name sortKey="Summerfield, Christopher" sort="Summerfield, Christopher" uniqKey="Summerfield C" first="Christopher" last="Summerfield">Christopher Summerfield</name></author><author><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name></author><author><name sortKey="Valls Ole, Josep" sort="Valls Ole, Josep" uniqKey="Valls Ole J" first="Josep" last="Valls-Solé">Josep Valls-Solé</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:DDFF490E0AC63254807278AC928917DF21B75C5D</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1002/mds.10638</idno><idno type="url">https://api.istex.fr/document/DDFF490E0AC63254807278AC928917DF21B75C5D/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001021</idno><idno type="wicri:Area/Istex/Curation">001021</idno><idno type="wicri:Area/Istex/Checkpoint">002707</idno><idno type="wicri:doubleKey">0885-3185:2004:Kumru H:effects:of:subthalamic</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:14743367</idno><idno type="wicri:Area/PubMed/Corpus">003570</idno><idno type="wicri:Area/PubMed/Curation">003570</idno><idno type="wicri:Area/PubMed/Checkpoint">003472</idno><idno type="wicri:Area/Ncbi/Merge">000C94</idno><idno type="wicri:Area/Ncbi/Curation">000C94</idno><idno type="wicri:Area/Ncbi/Checkpoint">000C94</idno><idno type="wicri:doubleKey">0885-3185:2004:Kumru H:effects:of:subthalamic</idno><idno type="wicri:Area/Main/Merge">005684</idno><idno type="wicri:source">INIST</idno><idno type="RBID">Pascal:04-0233624</idno><idno type="wicri:Area/PascalFrancis/Corpus">002226</idno><idno type="wicri:Area/PascalFrancis/Curation">000A95</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">002162</idno><idno type="wicri:doubleKey">0885-3185:2004:Kumru H:effects:of:subthalamic</idno><idno type="wicri:Area/Main/Merge">005A00</idno><idno type="wicri:Area/Main/Curation">003D26</idno><idno type="wicri:Area/Main/Exploration">003D26</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Effects of subthalamic nucleus stimulation on characteristics of EMG activity underlying reaction time in Parkinson's disease</title><author><name sortKey="Kumru, Hatice" sort="Kumru, Hatice" uniqKey="Kumru H" first="Hatice" last="Kumru">Hatice Kumru</name><affiliation><wicri:noCountry code="subField">Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS)</wicri:noCountry></affiliation></author><author><name sortKey="Summerfield, Christopher" sort="Summerfield, Christopher" uniqKey="Summerfield C" first="Christopher" last="Summerfield">Christopher Summerfield</name><affiliation><wicri:noCountry code="subField">Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS)</wicri:noCountry></affiliation></author><author><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name><affiliation><wicri:noCountry code="subField">Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS)</wicri:noCountry></affiliation></author><author><name sortKey="Valls Ole, Josep" sort="Valls Ole, Josep" uniqKey="Valls Ole J" first="Josep" last="Valls-Solé">Josep Valls-Solé</name><affiliation><wicri:noCountry code="subField">Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS)</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2004-01">2004-01</date><biblScope unit="vol">19</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="94">94</biblScope><biblScope unit="page" to="100">100</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">DDFF490E0AC63254807278AC928917DF21B75C5D</idno><idno type="DOI">10.1002/mds.10638</idno><idno type="ArticleID">MDS10638</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Brain Mapping</term><term>Choice Behavior (physiology)</term><term>Electric Stimulation</term><term>Electric Stimulation Therapy</term><term>Electromyography</term><term>Female</term><term>Functional Laterality (physiology)</term><term>Hand (innervation)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Muscle, Skeletal (innervation)</term><term>Nervous system diseases</term><term>Parkinson Disease (physiopathology)</term><term>Parkinson Disease (therapy)</term><term>Parkinson disease</term><term>Parkinson's disease</term><term>Pattern Recognition, Visual (physiology)</term><term>Psychomotor Performance (physiology)</term><term>Reaction Time (physiology)</term><term>Reaction time</term><term>Subthalamic Nucleus (physiopathology)</term><term>Subthalamic nucleus</term><term>Treatment Outcome</term><term>ballistic movements</term><term>deep brain stimulation</term><term>reaction time</term></keywords><keywords scheme="MESH" qualifier="innervation" xml:lang="en"><term>Hand</term><term>Muscle, Skeletal</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Choice Behavior</term><term>Functional Laterality</term><term>Pattern Recognition, Visual</term><term>Psychomotor Performance</term><term>Reaction Time</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Brain Mapping</term><term>Electric Stimulation</term><term>Electric Stimulation Therapy</term><term>Electromyography</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Treatment Outcome</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Electromyographie</term><term>Noyau sousthalamique</term><term>Parkinson maladie</term><term>Système nerveux pathologie</term><term>Temps réaction</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We examined the effects of high‐frequency deep brain stimulation of the subthalamic nucleus (STN‐DBS) on characteristics of electromyographic (EMG) activity of the agonist muscle in 8 patients with Parkinson's disease (PD). Patients were examined during STN‐DBS (ON), and 30 minutes after switching off both stimulators (OFF). They were asked to make a ballistic movement in paradigms of simple reaction time (SRT) and choice reaction time (CRT) tasks. Onset of movement (MOVonset) was measured as the latency of the initial displacement from baseline of the signal from an accelerometer attached to the dorsum of the hand. In the associated EMG activity, recorded from wrist extensor muscles, we measured onset latency (EMGonset), size of the first EMG burst (EMGsize), and number of EMG bursts (EMGbursts) counted between EMGonset and task execution. MOVonset and EMGonset were significantly shorter in ON than in OFF conditions in CRT. EMGsize was larger, EMGbursts were reduced, and peak of the acceleration profile was larger in ON compared with OFF conditions in both SRT and CRT. Our results indicate that STN‐DBS induces a significant improvement in motor performance of reaction time tasks in PD patients. Such improvement is associated with a change in features of the EMG activity suggesting an increase in the excitability of the motor pathways engaged in ballistic movements. © 2003 Movement Disorder Society</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Kumru, Hatice" sort="Kumru, Hatice" uniqKey="Kumru H" first="Hatice" last="Kumru">Hatice Kumru</name><name sortKey="Summerfield, Christopher" sort="Summerfield, Christopher" uniqKey="Summerfield C" first="Christopher" last="Summerfield">Christopher Summerfield</name><name sortKey="Valldeoriola, Francesc" sort="Valldeoriola, Francesc" uniqKey="Valldeoriola F" first="Francesc" last="Valldeoriola">Francesc Valldeoriola</name><name sortKey="Valls Ole, Josep" sort="Valls Ole, Josep" uniqKey="Valls Ole J" first="Josep" last="Valls-Solé">Josep Valls-Solé</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003D26 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 003D26 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:DDFF490E0AC63254807278AC928917DF21B75C5D
|texte= Effects of subthalamic nucleus stimulation on characteristics of EMG activity underlying reaction time in Parkinson's disease
}}
| This area was generated with Dilib version V0.6.23. |  |